Often during the mixing phase, I will sneak in some extra high-end on the EQ in an effort to bring out clarity in several instruments, (including vocals). Everything will sound great on my system. Then I play the song back on ear buds, or my phone, and realize the "esss's" and "teeee's" are waay too harsh. Like, ear bleeding harsh! A work around for taming them, without losing your clarity, is using a de'esser. Follow the link below for a free video instruction on setting up your de'esser and how to use it.
Mike Lizotte